July 2007 – KY SBIR/STTR Matching Funds Press Release
Naprogenix was one of twenty companies that were recipients of KY SBIR/STTR Matching Funds. In honor of these twenty companies, Kentucky’s Governor Ernie Fletcher and Commissioner for Department of Commercialization and Innovation Deborah Clayton ceremoniously awarded $1.875 million dollar check to all the representatives of the funded companies. Naprogenix’s received KY matching funds for our National Cancer Institute Phase I STTR on “Novel estrogen receptor ligands from plant genomics”. Both the Louisville Courier Journal and Lexington Herald Leader newspapers recognized Naprogenix as one of the awardees of this funding from the KY State Government.
Please click on links to review the news articles.
Louisville Courier Journal
Lexington Herald Leader

July 2007 – National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded Fast-Track STTR Grant on “Hypericum extracts as potential anti-relapse medications in alcoholism”

June 2007 – National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded Phase II STTR Grant on “Transgenic plant cells as a source of hepatoprotective drugs”

May 2007 – John M. Littleton, MD, PhD (Chief Biomedical Science Officer) published an article titled “The future of plant drug discovery” in Expert Opinion on Drug Discovery, May 2007, Vol. 2, No. 5, Pages 673-683. Please visit Expert Opinion Website at
http://www.expertopin.com/toc/edc/2/5 to obtain copies of Dr. Littleton’s article.

May 2007 – Deane L. Falcone, PhD (Chief Molecular Science) represented Naprogenix at BIO 2007 conference in Boston, MA. Dr. Falcone presented a poster on “A novel integrated strategy for plant drug discovery based on high throughput pharmacological screening (HTPS) and plant genomics” Click to see poster or abstract

January 2007 – Lexington Venture Club recognizes Naprogenix as one of the regional, early-stage companies that received funding in 2006. Click to see more details on the celebration at here.

Fall 2006 – Naprogenix was featured in the University of Kentucky College of Agriculture “the Magazine” article titled “Biotechnology – Moving Beyond the Lab”.

Click the links below to view the article as either pdf or html:

August 2006 - National Cancer Institute (NCI) awarded Phase I STTR Grant on “Novel estrogen receptor ligands from plant genomics”

January 2006 – Dr. Deane Falcone and Dr. John Littleton were awarded United States Patent 6,989,236 titled “Methods to identify plant metabolites”.

January 2006 – Kentucky Science & Technology Corporation awarded R&D Voucher on “Novel Active Insecticidal Compounds from Kentucky Native Plants”

Spring 2006 – The Lane Report’s Magazine featured Naprogenix in their annual “Research Kentucky” report. Please click on link to review report

Spring 2006 – Kentucky AgriTechnology Magazine featured Naprogenix in the article titled “Natural Products Research = New Crops for Kentucky Farms” Please click on link to review full article

January 2005 – Kentucky Science & Technology Corporation awarded R&D Voucher on “Application of NPG Technology to Alternate Plant Species”

September 2004 – National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded Phase I STTR Grant on “Potential anti-relapse drugs: a plant genomics approach”

June 2004 – National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded Phase I STTR Grant on “Application of plant genomics to alcoholic brain damage”

September 2003 – National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded Phase I STTR Grant on “Transgenic plant cells as a source of hepatoprotective drugs”

2003 – Naprogenix obtains the exclusive license agreement with the University of Kentucky on patented NPG technology.